Why We Sunburn

News | Health

A molecular signal that triggers sunburns helps the body remove sun-damaged cells before they trigger cancer. The findings could lead to new treatments for psoriasis and other inflammatory responses

By Rachael Rettner and MyHealthNewsDaily ?| July 9, 2012?|

Image: Flickr/kirinqueen

Sunburns readily advertise that we've had fun in the sun, and perhaps have been a bit careless, but what exactly goes on in our cells to produce the painful, red inflammation has not been clear.

Now, researchers have discovered a molecular signal that triggers sunburns.

When our skin cells are exposed to ultraviolet B (UVB) radiation , a specific form of RNA, called micro-RNA, is damaged, the study found. (RNA is similar in structure to DNA, which makes up our genes.)

This damaged RNA is then released as a signal of solar injury, and prompts neighboring, healthy cells to stimulate the production of factors that promote inflammation, the researchers said.

The entire process is intended to remove sun-damaged cells, which could turn cancerous if not cleared away.

"The cells of our skin can sense dead, [sun-damaged] cells, because the cells release damaged RNA," said study researcher Dr. Richard Gallo, professor of medicine at University of California, San Diego School of Medicine.

While other factors likely play a role in the inflammatory process we see as a sunburn, the findings suggest the damaged RNA molecules serve as a marker for radiation-caused injury, the researchers said. [Why Sunburns Hurt]

The findings may have implications for medical conditions, the researchers said.

For example, one treatment for the skin condition psoriasis is exposure to UV light. But while the light can relieve symptoms, it also increases skin cancer risk, Gallo said. The new findings suggest that certain RNA molecules could be used in place of UV therapy, and produce the same benefit, Gallo said.

In addition, people with certain autoimmune conditions get a burning sensation with very little exposure to UV light, before unhealthy cell damage has occurred, Gallo said. Blocking the micro-RNA pathway may be a way to reduce inflammation in these patients, Gallo said.

However, healthy people without such conditions would not want to block this pathway just to prevent sunburn, because it is an important way for the body to heal and get rid of damaged cells, Gallo said.

"The inflammatory response is a normal part of our protection against the sun," Gallo said.

The study is published online today (July 8) in the journal Nature Medicine.

Pass it on:? Damaged RNA molecules released from sun-damaged cells are one molecular trigger of sunburns.

Follow MyHealthNewsDaily on Twitter @MyHealth_MHND. We're also on Facebook & Google+.

Copyright 2012 MyHealthNewsDaily, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://rss.sciam.com/click.phdo?i=af29f600a366ad704c45361b0e50c133

beasley trailblazers michael beasley jermaine jones

BUILD YOUR SELF ESTEEM, A STARTER GUIDE TO SELF ...

So how do you stay calm, composed and maintain self esteem in a tough environment? Here are some tips you may to consider as a starter guide to self improvement.

Imagine yourself as a Dart Board. Everything and everyone else around you may become Dart Pins, at one point or another. These dart pins will destroy your self esteem and pull you down in ways you won?t even remember. Don?t let them destroy you, or get the best of you. So which dart pins should you avoid?

Dart Pin #1 : Negative Work Environment
Beware of ?dog eat dog? theory where everyone else is fighting just to get ahead. This is where non-appreciative people usually thrive. No one will appreciate your contributions even if you miss lunch and dinner, and stay up late. Most of the time you get to work too much without getting help from people concerned. Stay out of this, it will ruin your self esteem. Competition is at stake anywhere. Be healthy enough to compete, but in a healthy competition that is.

Dart Pin #2: Other People?s Behavior
Bulldozers, brown nosers, gossipmongers, whiners, backstabbers, snipers, people walking wounded, controllers, naggers, complainers, exploders, patronizers, sluffers? all these kinds of people will pose bad vibes for your self esteem, as well as to your self improvement scheme.

Dart Pin #3: Changing Environment
You can?t be a green bug on a brown field. Changes challenge our paradigms. It tests our flexibility, adaptability and alters the way we think. Changes will make life difficult for awhile, it may cause stress but it will help us find ways to improve our selves. Change will be there forever, we must be susceptible to it.

Dart Pin #4: Past Experience
It?s okay to cry and say ?ouch!? when we experience pain. But don?t let pain transform itself into fear. It might grab you by the tail and swing you around. Treat each failure and mistake as a lesson.

Dart Pin #5: Negative World View
Look at what you?re looking at. Don?t wrap yourself up with all the negativities of the world. In building self esteem, we must learn how to make the best out of worst situations.

Dart Pin #6: Determination Theory
The way you are and your behavioral traits is said to be a mixed end product of your inherited traits (genetics), your upbringing (psychic), and your environmental surroundings such as your spouse, the company, the economy or your circle of friends. You have your own identity. If your father is a failure, it doesn?t mean you have to be a failure too. Learn from other people?s experience, so you?ll never have to encounter the same mistakes.

Sometimes, you may want to wonder if some people are born leaders or positive thinkers. NO. Being positive, and staying positive is a choice. Building self esteem and drawing lines for self improvement is a choice, not a rule or a talent. God wouldn?t come down from heaven and tell you ? ?George, you may now have the permission to build self esteem and improve your self.?

In life, its hard to stay tough specially when things and people around you keep pulling you down. When we get to the battle field, we should choose the right luggage to bring and armors to use, and pick those that are bullet proof. Life?s options give us arrays of more options. Along the battle, we will get hit and bruised. And wearing a bullet proof armor ideally means ?self change?. The kind of change which comes from within. Voluntarily. Armor or Self Change changes 3 things: our attitude, our behavior and our way of thinking.

Building self esteem will eventually lead to self improvement if we start to become responsible for who we are, what we have and what we do. Its like a flame that should gradually spread like a brush fire from inside and out. When we develop self esteem, we take control of our mission, values and discipline. Self esteem brings about self improvement, true assessment, and determination. So how do you start putting up the building blocks of self esteem? Be positive. Be contented and happy. Be appreciative. Never miss an opportunity to compliment. A positive way of living will help you build self esteem, your starter guide to self improvement.

Source: http://life-health-happiness.com/?p=12559

rob lowe peyton manning what is sopa marianne gingrich ibooks author gabrielle union

mobile cell phone jammer wireless department's merger and into ...

At the same time, with lenovo mobile phone launched the K800, Intel announced formally into mobile phone chips field, this also is Intel company six years later returned to the field, and to emphasize its mobile chip products in high performance computing and process has absolute advantage.
On Dec. 15, 2011, Intel announced the formation of a new mobile communications department, the new department before the Internet from and tablet computer department, super mobile department, mobile communications departments and mobile cell phone jammer wireless department?s merger and into.
?This is to speed up and improve the product development process.? Intel spokesman Robert many tower said, before the merger, mobile wireless departments responsible for including Wi-Fi, short of network, and the department was responsible for developing intelligent mobile phone chips.
As the PC era of chip overlord, Intel is still dominated the global PC market share of about 80%. But in the smart phone and tablet markets, ARM architecture chip account for 80% of the market share?from apple, Samsung (Samsung) to HTC electricity (HTC) smart phone, even LianFa secco fortress machine, want to pay to ARM.
For Intel high-key enter phone chip market, ARM company vice President, processor and intellectual property department general manager Simon, and, with a short term that does not have competitive advantage, ?can?t shake in mobile chip ARM the leading position in the field of?.
No matter how for low cost of the smart cell phone jammer market chipsets competition will be more intense, credit suisse analyst Taipei, Randy Abrams (Randy Abrams) says, because the entry-level smart phone meager margins, chip manufacturers will be through the sales to ensure that profits.
The figures show, nokia? s share price than revenue also hit a historical minimum level, lower than any other global market value at least $5 billion communications equipment manufacturer.
At the same time, as of March 31, nokia holds cash and short-term investments totaling us $12.4 billion and $8.6 billion so far higher than by yesterday?s market value. After deducting debt later, nokia? s net cash amount of $5.9 billion, equivalent to 68% of the cell phone jammer company still market value.
Falcon Point Capital senior managing director Mahanoy pointed out: ?nokia, more than half of the market value is cash, this means that whatever the situation, the company is how cheap.? For private equity company for, nokia has ?is cheap enough to this level. When, don?t even need to reduce the cost of many from the takeover value for.?
Avian Securities investment company in Boston, the analysts Matt Thornton (Matt Thornton, pointed out that private-equity firms may be interested in the main mobile phone business acquisition nokia for its advanced, and nokia Siemens the joint venture may be sold or split into an independent of the listed companies.

Source: http://www.phone-jammer.org/mobile-cell-phone-jammer-wireless-department%E2%80%99s-merger-and-into/

california earthquake california earthquake tyson chandler tyson chandler stephen hill draft tracker the pirates band of misfits

Battle of the Snoring Sexes - Women's health | Beauty

It is a common sight, seeing men and women argue endlessly about who does this or that better and faster. But when it comes to snoring, no one is in a hurry to claim superiority.

Here is the undeniable truth: both men and women snore. However, snoring tends to be more prevalent in men than in women. In fact, studies have shown that men snore twice as much as women do. What is the reason behind this?

One reason could be that alcohol intake is higher in men than in women. Alcohol has been known to loosen the throat and tongue muscles, thus increasing the possibilities of snoring. The same is true for smoking as the throat also becomes relaxed when exposed to smoke. Aside from exposure to smoke, smoking also leads to lung and nasal congestion, and these cause blockages or obstruction in the airways, eventually leading to snoring. Generally, men smoke more than women.

Alcohol and smoking aside, however, the higher rate of snoring among men can be blamed on anatomical factors. The air passages of men are naturally smaller than that of women. A smaller airway means a narrower passageway for air to pass through so that, during sleep, breathing becomes more difficult.

The position of the tongue also has a huge role when it comes to snoring. A tongue that is positioned incorrectly can become a breathing obstruction during sleep. Ideally, men?s jaws are designed to be more defined. As a result, their jaws tend to be smaller or narrower, giving not a lot of ?leg room? for the tongue. Cramped, the tongue would fall back and interferes with the normal breathing process. If you compare this with women?s jaws that tend to be recessed, the tongue is positioned more correctly, thus reducing the chances of snoring.

Women are as guilty of snoring as men. Hormonal levels can often be blamed for snoring in women. This is the reason why snoring often becomes more pronounced during pregnancy since the rise of their estrogen levels cause the soft tissues in their throat to swell. This swelling leads to snoring since it causes interference with the normal breathing process during sleep.

Women are also more prone to obesity than men, and obesity is known to be one of the underlying conditions that lead to snoring. Granted, men are also not impervious to being overweight. This is why it is important for everybody to take care of their bodies and their health, regardless of their gender.

Both men and women snore, and they could go on and on arguing who snores more often or louder. However, they are missing the point. They should look past the gender issues in relation to snoring and pay more attention on the causes, the risks, and the effects of their snoring problem. More than saving face, it might actually be what will save their lives.

If your looking for natural ways on how to stop snoring, try the Good Night Anti Snore Ring which acupressure on your little finger to reduce and stop snoring. Complete with a 30 day money back guarantee.

Source: http://www.womenfavor.com/battle-of-the-snoring-sexes.html

kim mulkey sarah palin today show dallas tornado video 1940 census instagram for android dallas news dallas fort worth

Personal Development Air Jordan Tips To Help You Turn Into A ...

A lot of people aim to process personal development. Personal development allows men and women enhance on their own Air Jordan because they build on the all-natural features. Self improvement could be effortless or difficult, depending on what factor you try to develop. The tips in the following article need to aid you with your very own growth.

It is imperative that you invest in maintaining your awesome in the inclusion of other people. Enabling you to ultimately blow up and get rid of manage might have disastrous effects on the standard of your relationships and your track record at home, university, or at work. Normal outbursts can rapidly result in your friends to place up protective shields close to you for fear of illumination your fuse.

A great hint for private development would be to by no means quit. Irrespective of how hard your objectives are, you need to in no way cease upon them. A lot of people fail at their goals because they offered up. Even so, those who become successful at their set goals are those who never ever stop through the terrible Jordan Femme periods. They bound to their set goals and in the end succeeded.

When confronted with the self help processes for nervousness, you should find a thing that gives you calm and comforting feelings. With out a delivering believed, the stress and anxiety may develop till you have an anxiety invasion. using these quiet and soothing feelings you gradual your coronary heart and anxious opinions.

Creating a collection of the things that represent what you are trying for inside your self improvement can help you keep on monitor. You possibly can make an Air Jordan Pas Cher collage by looking at older issues of the favored publications, cutting words and phrases and pictures that happen to be purposeful in your desired goals, and gluing them to a sheet of pieces of paper. Position it near your bed furniture so you?ll view it every morning and evening for a visible note of your self improvement goals.

Make your desired goals in mind. You are going to more inclined grow to be preoccupied or perhaps discouraged at some point or some other. Make sure you have anything to keep you on the right course over these moments. Probably other people can assist you, or you can use certain things or places to help remind you of what you need, and the reason why you want to buy.

Accept change. Alter is among the most continual things about a persons encounter. Feel how far mankind comes, and you?ll Air Jordan Pas Cher feel happier about your personal ability to adapt when the scenario calls for it. Reminisce how considerably you?ve already can come and get excited about the ways you?ll change down the road.

Get out of the house at the very least for a bit each day. Isolating yourself within the home isn?t healthy and may aggravate depressive disorders. Even when it?s something as simple as resting outdoors on the deck for a few minutes or so every day, it may help your battle with despression symptoms.

As stated before, many look for personal development. It enables individuals develop normal qualities Air Jordan to improve them selves. According to the feature you would like to develop, personal development may be straightforward or difficult. Nonetheless, with the recommendations using this post that will help you, you ought to discover self improvement a little easier.

Recognized Air Jordan Pas Cher Store provides you numerous inexpensive Jordan Femme Shoes right now with Fast Delivery service, Score Payment & Incredible Customer Support.

Source: http://iwebdeveloper.co.uk/2012/07/06/personal-development-air-jordan-tips-to-help-you-turn-into-a-much-better-person/

obama birth control mortgage settlement macauly culkin joe namath stefon diggs nazi ss andrej pejic

Three kids dead after yacht capsizes off Long Island

Police say a massive wave may have knocked 27 people from a yacht during an Independence Day celebration near New York's Long Island, leading to the drownings of three children. WNBC's Jonathan Vigliotti reports.

By NBCNewYork.com

Three children died and 24 other people were rescued after being pulled from the Long Island Sound after their yacht capsized on the Fourth of July, Nassau County police say.

Authorities say the group had been out watching fireworks on Oyster Bay to celebrate Independence Day when tragedy struck. The cause of the capsize is under investigation, though officials believe weather, overcrowding or a massive wave from the wake of another boat may have been factors.

---

Nassau County Deputy Inspector Kenneth Lack said two of the child victims were recovered from inside the sunken yacht after a long overnight search. Another was pulled from the water Wednesday night. The victims were?David Aurelino, 12, Harley Treanor, 11, and Victoria Gaines, 8.

Authorities said the boat party was a group of family members and friends who were returning from a fireworks display when their vessel capsized and began sinking. Two people were operating the boat, and investigators say there is no evidence they were intoxicated when the accident happened.

Someone called 911 just after 10 p.m. Wednesday to report the accident, and nearby civilian watercraft helped officials in the rescue effort.

For more, visit NBCNewYork.com

The U.S. Coast Guard says survivors were pulled from the water after the 34-foot Silverton capsized. All 27 passengers had been in the water at one point, police said. Most of them were taken aboard other crafts very quickly, he said.?

Police say the rescue operation was hampered by the number of victims in the water, the time of day and the number of boats out celebrating the holiday.

Lack says some but not all passengers had been wearing life jackets. Authorities said part of their investigation would delve into whether there were enough life jackets on the yacht for all the passengers, which is required. It's also required that anyone younger than age 12 have a life jacket on when outside the boat's cabin.

A special marine warning was in effect for that particular area of the Long Island Sound late Wednesday night. Radar captured between 10:30 p.m. and 11 p.m. showed a severe thunderstorm crossing Oyster Bay with winds of up to 40 mph.

Coast Guard Petty Officer Anthony Kozak said the Silverton yacht was submerged about 60 feet under water three miles off the coast of Oyster Bay.

More content from msnbc.com and NBC News:

Follow US News on msnbc.com on Twitter and Facebook

?

Source: http://usnews.msnbc.msn.com/_news/2012/07/05/12574045-three-kids-dead-after-yacht-capsizes-off-long-island-new-york?lite

ireland bracket vangogh yield crossbow airhead atherosclerosis

Really? Mermaids don't exist, NOAA website notes

The National Ocean Service's June 27 posting that mermaids don't exist may seem an odd fit for a government agency that focuses on real ocean phenomena. But according to a spokesperson the mermaid posting is just one way to educate people, and perhaps bust some mermaid myths.

The timing of the post seems to coincide with the Animal Planet show "Mermaids: The Body Found," which came out at the end of May and explored whether there is "a kernel of truth that lives beneath the legend of the mythic mermaid," according to the show's description.

Not so, says the National Ocean Service (part of the National Oceanic and Atmospheric Administration, NOAA). "No evidence of aquatic humanoids has ever been found," part of the post reads. Nevertheless, a NOAA spokesperson would not confirm that the post was in direct response to the show, which was presented in documentary format.

1. More science news from msnbc.com

   1. Higgs boson quest turns up new particle

      Scientists say they've discovered a type of particle that's never been seen before ? a particle that mostly matches the description of the fabled Higgs boson.

   2. Updated 44 minutes ago 7/4/2012 9:17:48 PM +00:00 Theorist Peter Higgs lives to see his boson
   3. Scientists capture shadow cast by a single atom
   4. Really? Mermaids don't exist, NOAA website notes

The reference to "aquatic humanoids" alludes to a controversial theory called the aquatic ape theory, which suggests humans had an aquatic stage in our evolutionary past. Called "pseudoscience" by anthropologist John Hawks on his blog, this theory is not supported by most scientists.?

The Animal Planet summary says its show is "a story about evolutionary possibility grounded in a radical scientific theory ? the Aquatic Ape Theory, which claims that humans had an aquatic stage in our evolutionary past."

The mermaids post is part of the Ocean Facts section of the National Ocean Service website to answer inquiries they receive. Since October 2008, they have posted 195 ocean facts items.

"The timing was around that time. I think the TV show came out around Memorial Day and we got a few of the questions [about mermaids]," Keeley Belva, spokesperson for NOAA's National Ocean Service, told LiveScience. "Arguably, yes, the timing is tied to the documentary."

She added, "As we had gotten a couple questions about mermaids, we thought this would be a fun way to talk about it and to have information up about mermaids in different cultures and to draw people into our website and learn more about what NOAA and the National Ocean Service does." [ Top 10 Mythical Creatures ]

In popular myth, mermaids are half-human, half-fish sirens of the sea. As the ocean facts post points out, they "are legendary sea creatures chronicled in maritime cultures since time immemorial." For instance, Homer wrote of them in the ancient Greek epic "The Odyssey," and in the Far East, mermaids were considered the wives of powerful sea dragons, serving as trusted messengers between the spouses and emperors of the land.

In fact, the scientific grouping Sirenia, which includes manatees and their close relative the dugong comes from mermaid legend. Sailors long ago mistook these large gentle marine mammals for mermaids, or sirens who sang songs to lure ships into rocky shores. Legend has it that Christopher Columbus recorded a sighting of a manatee, saying he was surprised at the not-so-beautiful "mermaid," according to the Dolphin Research Center in Florida.

The aboriginal people of Australia had their own name for mermaids, yawkyawks, which could refer to the sirens' allegedly mesmerizing songs. In fact, as far back as 30,000 years ago when humans were becoming the dominant species of the land, and possibly taking to the seas, they seem to have imagined magical female figures. These figures first appear in cave paintings at the time.

"Half-human creatures, called chimeras, also abound in mythology ? in addition to mermaids, there were wise centaurs, wild satyrs, and frightful minotaurs, to name but a few," according to the NOAA Web posting.

Even today, "mermaid" sightings still occur. For instance, in 2009 in the Israeli town of Kiryat Yam, locals and tourists flocked to the coast in hopes of glimpsing an alleged mermaid that resembled a cross between a fish and a young girl; apparently she would only appear at sunset.

Follow LiveScience on Twitter @livescience. We're also on Facebook & Google+.

? 2012 LiveScience.com. All rights reserved.

Source: http://www.msnbc.msn.com/id/48065838/ns/technology_and_science-science/

city creek center andrew luck pro day josh johnson kim kardashian flour matt forte jeremy shockey new orleans saints